UPDATE (3:15 p.m., June 26, 2021): Authorities confirmed Saturday afternoon that an Amber Alert has been canceled for two missing children from Moore.

The children, 6-year-old Kathryn Glad and 2-year-old Cory Glad, are safe and have been located. Authorities also said they have a suspect in custody.

The suspect and children were found at a Holiday Inn next to the Oklahoma Aquarium in Jenks.

Below is the original story.

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An Amber Alert has been issued for two missing children.

Oklahoma Highway Patrol said 6-year-old Kathryn Glad and her 2-year-old brother Cory were taken by their grandmother Twana Brinlee in Moore. Brandon Glad, the father of the children, said Brinlee has schizophrenia and this is not the first time they have had issues with her.

"About two years ago she pinned down my oldest child to the floor and held a cross over his head, claiming that he was possessed by the devil because he was making growling sounds," Brandon Glad said.

Troopers said they are also concerned she may be armed and unmedicated. Police are looking for a gray new model Toyota Tacoma with the license KBQ254.

Troopers said they may be heading toward Arkansas.